Research skills

Predicts ADMET properties using ADMETlab 3.0 (119 endpoints with uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles,...

Process many FASTA/FASTQ/GenBank files in batch — merge, split, convert, summarize, organize — using Biopython 1.83+.

Align Illumina short reads to a reference genome with BWA-MEM — including index, MEM algorithm, paired-end, alt-contig handling, and 2026 best practices.

Use BWA-MEM2 — the SIMD-accelerated BWA-MEM replacement — for 2-3x speedup on human genome alignment with identical results to BWA-MEM.

Compute codon usage frequencies, RSCU, CAI, and tRNA adaptation — for gene expression prediction, heterologous expression design, and comparative genomics.

Read and write gzip, bzip2, and BGZF-compressed FASTA/FASTQ using Python stdlib and Biopython — including indexable BGZF.

Access, filter, and trim Phred quality scores in FASTQ reads using Biopython 1.83+ — including per-position profiles and encoding auto-detection.

Filter FASTA/FASTQ records by length, identity, regex on headers, GC window, complexity, and custom predicates — streaming with Biopython 1.83+.

Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting...

Queries the NCATS Translator ARAX production API for bounded, typed, provenance-rich one-hop and endpoint-pinned two-hop biomedical knowledge-graph relationships. Use for...

Resolve free-text scientific labels to ontology term IDs and validate existing CURIEs against the EBI Ontology Lookup Service (OLS4). Use whenever an ontology identifier must be...

Search and read full-text biomedical papers, FDA/PMDA/EMA regulatory documents, clinical trial registries, and UniProt/PDB/ChEMBL entries with the Paperclip CLI from GXL. Covers...

Plan, execute, and document validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP <1220>/<1225>/<1226>, ICH M10...

Single-coin comprehensive analysis. Use this skill ONLY when the user asks to analyze one coin with no additional explicit dimension (e.g., no separate risk check, no separate...

Coin comparison. Use this skill whenever the user asks to compare two or more coins. Trigger phrases include: compare, versus, vs, which is better, difference. MCP tools:...

Market overview. Use this skill ONLY when the user's query is exclusively about overall market conditions with no specific coin analysis. Trigger phrases: how is the market,...

Use this skill whenever the user wants Gate.info / Gate.news research via gate-cli: single-coin, market overview, multi-coin compare, TA, macro, or research+news. Trigger phrases...

News briefing. Use this skill ONLY when the user's query is exclusively about recent news or headlines with no other analysis dimensions. Trigger phrases: what happened recently,...

Community sentiment via Gate-News MCP, X/Twitter-first. Use for social discussion, KOL takes, or opinion on a coin or topic. Triggers: what does the community think about ETH,...

Event attribution and explanation. Use this skill ONLY when the user's query is exclusively about the reason behind a price move with no other analysis dimensions. Trigger...

Use this skill whenever the user’s main ask is news, events, listings, social/UGC, or market move attribution. Primary gate-cli news (optional info for market context). Covers...

Exchange listing tracker. Use this skill whenever the user asks about exchange listing, delisting, or maintenance announcements. Trigger phrases include: any new coins listed...

以证据为先的ECC当前状态研究工作流程。当用户希望基于当前公开证据和提供的本地上下文获取最新事实、比较、丰富信息或建议时使用。

研究优先于编码的工作流程。在编写自定义代码之前，搜索现有的工具、库和模式。调用研究员代理。