OMadmet-predictionpradyumnasagar-open-research-skills#ors-metaResearchcheminformaticsdrug discoveryqsar-modelingPredicts ADMET properties using ADMETlab 3.0 (119 endpoints with uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles,...
OMbatch-processingpradyumnasagar-open-research-skills#ors-metaResearchbioinformaticsdata pipelinessequence processingProcess many FASTA/FASTQ/GenBank files in batch — merge, split, convert, summarize, organize — using Biopython 1.83+.
OMbwa-alignmentpradyumnasagar-open-research-skills#ors-metaResearchbioinformaticsgenomicssequence alignmentAlign Illumina short reads to a reference genome with BWA-MEM — including index, MEM algorithm, paired-end, alt-contig handling, and 2026 best practices.
OMbwa-mem2-alignmentpradyumnasagar-open-research-skills#ors-metaResearchbioinformaticsgenomicssequence alignmentUse BWA-MEM2 — the SIMD-accelerated BWA-MEM replacement — for 2-3x speedup on human genome alignment with identical results to BWA-MEM.
OMcodon-usagepradyumnasagar-open-research-skills#ors-metaResearchbioinformaticsgenomicssequence analysisCompute codon usage frequencies, RSCU, CAI, and tRNA adaptation — for gene expression prediction, heterologous expression design, and comparative genomics.
OMcompressed-sequence-filespradyumnasagar-open-research-skills#ors-metaResearchpythonbioinformaticsbiopythonRead and write gzip, bzip2, and BGZF-compressed FASTA/FASTQ using Python stdlib and Biopython — including indexable BGZF.
OMfastq-quality-scorespradyumnasagar-open-research-skills#ors-metaResearchpythonbioinformaticssequence analysisAccess, filter, and trim Phred quality scores in FASTQ reads using Biopython 1.83+ — including per-position profiles and encoding auto-detection.
OMfilter-sequencespradyumnasagar-open-research-skills#ors-metaResearchbioinformaticsgenomicsbiopythonFilter FASTA/FASTQ records by length, identity, regex on headers, GC window, complexity, and custom predicates — streaming with Biopython 1.83+.
SAliterature-reviewK-Dense-AI-scientific-agent-skills#scientific-agent-skillsResearchliterature reviewsystematic reviewcitation verificationConduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting...
SAncats-araxK-Dense-AI-scientific-agent-skills#scientific-agent-skillsResearchprovenanceAPI clientbiomedical knowledge graphQueries the NCATS Translator ARAX production API for bounded, typed, provenance-rich one-hop and endpoint-pinned two-hop biomedical knowledge-graph relationships. Use for...
SAontology-term-resolutionK-Dense-AI-scientific-agent-skills#scientific-agent-skillsResearchontology lookupmetadata annotationterm validationResolve free-text scientific labels to ontology term IDs and validate existing CURIEs against the EBI Ontology Lookup Service (OLS4). Use whenever an ontology identifier must be...
SApaperclipK-Dense-AI-scientific-agent-skills#scientific-agent-skillsResearchbiomedical-literaturesemantic searchregulatory documentsSearch and read full-text biomedical papers, FDA/PMDA/EMA regulatory documents, clinical trial registries, and UniProt/PDB/ChEMBL entries with the Paperclip CLI from GXL. Covers...
SAanalytical-method-validationK-Dense-AI-scientific-agent-skills#scientific-agent-skillsResearchregulatory complianceanalytical-chemistrymethod-validationPlan, execute, and document validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP <1220>/<1225>/<1226>, ICH M10...
GSgate-info-coinanalysisgate-gate-skills#gate-skillsResearchmarket-datanews aggregationcryptocurrency analysisSingle-coin comprehensive analysis. Use this skill ONLY when the user asks to analyze one coin with no additional explicit dimension (e.g., no separate risk check, no separate...
GSgate-info-coincomparegate-gate-skills#gate-skillsResearchcryptocurrencycoin comparisonmarket snapshotCoin comparison. Use this skill whenever the user asks to compare two or more coins. Trigger phrases include: compare, versus, vs, which is better, difference. MCP tools:...
GSgate-info-marketoverviewgate-gate-skills#gate-skillsResearchcrypto marketmarket overviewmarket briefingMarket overview. Use this skill ONLY when the user's query is exclusively about overall market conditions with no specific coin analysis. Trigger phrases: how is the market,...
GSgate-info-researchgate-gate-skills#gate-skillsResearchmarket analysisCLI tooltechnical analysisUse this skill whenever the user wants Gate.info / Gate.news research via gate-cli: single-coin, market overview, multi-coin compare, TA, macro, or research+news. Trigger phrases...
GSgate-news-briefinggate-gate-skills#gate-skillsResearchmarket intelligencesocial sentimentnews briefingNews briefing. Use this skill ONLY when the user's query is exclusively about recent news or headlines with no other analysis dimensions. Trigger phrases: what happened recently,...
GSgate-news-communityscangate-gate-skills#gate-skillsResearchcryptocurrencynews aggregationcommunity sentimentCommunity sentiment via Gate-News MCP, X/Twitter-first. Use for social discussion, KOL takes, or opinion on a coin or topic. Triggers: what does the community think about ETH,...
GSgate-news-eventexplaingate-gate-skills#gate-skillsResearchmarket analysisnews analysisevent attributionEvent attribution and explanation. Use this skill ONLY when the user's query is exclusively about the reason behind a price move with no other analysis dimensions. Trigger...